Fresh from a triumphant battle over the zombie horde that invaded London, vampire William Shakespeare concocts a plot to rid the love of his life from the encumbrance of her husband. Will plans to give his "dark lady," Katherine Dymond, a potion that will make her sleep the sleep of the dead. Once she is entombed, Will can sneak in, wait for her to awaken, then spirit her away. After her husband returns to his plantation in America, Kate can return to London under a different name and assume a new identity. No one will believe that the dead Katherine and the live Kate are the same woman.

Of course, as is often the case with true love, all does not go as smoothly as planned. When the two of them are shipwrecked on an island ruled by a wizard and a nymph, as well as infested by zombies, Will and Kate must stop an even larger plot afoot: a plot that leads all the way to the royal palaces of Queen Elizabeth.