Young, overworked, overtired, overstressed medical intern Sarah James has no time for sleuthing. Her elderly neighbors, the spunky Fog Ladies, have nothing but time. When, one by one, old ladies die in their elegant apartment building in San Francisco, Sarah assumes it is the natural consequence of growing old. The Fog Ladies assume murder.

Mrs. Bridge falls off a stool cleaning bugs out of her kitchen light. Mrs. Talwin hits her head in the bathtub and drowns. Suddenly, the Pacific Heights building is turning over tenants faster than the fog rolls in on a cool San Francisco evening.

Sarah resists the Fog Ladies' perseverations. But when one of them falls down the stairs and tells Sarah she was pushed, even Sarah believes evil lurks in their building. Can they find the killer before they fall victim themselves?