San Jose Police Lieutenant Frank Foley faces one of the most difficult cases of his storied career: a serial killer who brutally dismembers his victims. Worse, he leaves behind little evidence, and his MO changes with each victim.

Meanwhile, a number of ordinary people begin to experience unsettling changes within themselves that lead them on different journeys, and they discover that super powers aren't always what they're cracked up to be. Enhanced senses come with a downside that makes them desperate, or worse, drives them mad.

As Frank and his partner work to solve the Ripper Murders, he crosses paths with these so-called Sensitives, and struggles to come to terms with his own secrets that threaten to unravel his whole life.