Cassie Chambers grew up in Eastern Kentucky. A lawyer and the vice chair of the Kentucky Democratic Party, she graduated from Yale College, the Yale School of Public Health, the London School of Economics, and Harvard Law School, where she was president of the Harvard Legal Aid Bureau, a student-run law firm that represents low-income clients. Chambers then received a Skadden Fellowhship to return to Kentucky to work with domestic violence survivors in rural communities. She lives in Louisville with her husband.